YFP_quenching_assay_data

Figshare2023-08-09 更新2026-04-28 收录

纤维化治疗

离子通道功能检测

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https://figshare.com/articles/dataset/YFP_quenching_assay_data/23907711 数据链接链接失效反馈

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Data for manuscript: Gain-of-function CFTR restores essential epithelial function with greater efficacy than wildtype or codon optimized CFTR when expressed in cystic fibrosis airway cells.

创建时间：

2023-08-09

Cyclic Peptidyl Inhibitors against CAL/CFTR Interaction for Treatment of Cystic Fibrosis

纤维化治疗

CFTR药物研究

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding for a chloride ion channel. Membrane expression of CFTR is negatively regul

NIAID Data Ecosystem70

Administration of glutaredoxin-1 attenuates liver fibrosis caused by aging and non-alcoholic steatohepatitis. Administration of glutaredoxin-1 attenuates liver fibrosis caused by aging and non-alcoholic steatohepatitis

纤维化治疗

非酒精性脂肪性肝炎

Glutaredoxin-1 (Glrx) controls redox signaling and has an anti-apoptotic function. We evaluated the role of Glrx on hepatic cell damage and fibrosis induced by a high-fat diet. We fed mice a high-fat

NIAID Data Ecosystem30

DataSheet_1_Huangkui Capsule Ameliorates Renal Fibrosis in a Unilateral Ureteral Obstruction Mouse Model Through TRPC6 Dependent Signaling Pathways.zip

纤维化治疗

TRPC6信号通路

Renal fibrosis is the final common pathological manifestation of almost all progressive chronic kidney diseases (CKD). Transient receptor potential canonical (TRPC) channels, especially TRPC3/6, were

NIAID Data Ecosystem20

nNO measurements before and after two months and one year of ivacaftor therapy.

纤维化治疗

呼吸道疾病监测

nNO measurements before and after two months and one year of ivacaftor therapy.

NIAID Data Ecosystem50

Summary of adverse events that occurred in >5% of patients in any treatment group (treated set).

临床药物安全性

纤维化治疗

*The preferred adverse event term used for “CF exacerbation” was “cystic fibrosis.”A patient may have been counted in more than one preferred term. Percentages were calculated using the total number o

Figshare2015-12-02 更新30

YFP_quenching_assay_data

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