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INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z111810692

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Protein Data Bank Japan2026-02-18 更新2026-03-21 收录
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INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z111810692 Descriptor: DIMETHYL SULFOXIDE, N-(3-chlorophenyl)-2,2,2-trifluoroacetamide, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Authors: Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.33 Å) Cite: Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024

INPP5D PanDDA分析组提交数据集——SHIP1磷酸酶结构域与C2结构域结合Z111810692的共晶结构。试剂清单:二甲基亚砜(DIMETHYL SULFOXIDE)、N-(3-氯苯基)-2,2,2-三氟乙酰胺、磷脂酰肌醇3,4,5-三磷酸5-磷酸酶1(Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1)。作者:Bradshaw, W.J.、Newman, J.A.、von Delft, F.、Arrowsmith, C.H.、Edwards, A.M.、Bountra, C.、Gileadi, O.。提交日期:2020-10-30;发布日期:2020-11-11;最后修改日期:2026-02-18。实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.33埃(Å)。引用文献:《通过SHIP1与SHIP2的C2结构域调控肌醇5-磷酸酶活性》(Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2),《Structure》期刊,2024年
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2020-10-30
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