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BCR-ABL1 and a dominant negative isoform of Ikaros cooperate to induce human acute myeloid leukemia

ChEBI2014-05-23 更新2026-07-21 收录

急性髓系白血病

癌基因协同作用

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-45452 数据链接链接失效反馈

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资源简介：

BCR-ABL1 and a dominant negative isoform of Ikaros cooperate to induce human acute myeloid leukemia

应用场景：

创建时间：

2014-05-23

急性髓系白血病

耐药性机制

Targeting the MYST acetyltransferases are an exciting therapeutic opportunity in acute myeloid leukaemia (AML). Here we define the individual and combined contribution of KAT6A, KAT6B and KAT7, in ran

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Kynurenine engages Serotonin Receptor 1b in osteoblasts to reinforce Acute Myeloid Leukemia

急性髓系白血病

白血病研究

We performed RNAseq analysis of primary human osteoblasts co-cultured with the human THP-1 AML cell-line and, in parallel, RNAseq analysis on the THP-1 AML cells exposed to the human primary osteoblas

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Role of Branched Chain Amino Acid Transaminase 1 (BCAT1) in Acute Myeloid Leukemia [expression_BCAT1-KD #2]

急性髓系白血病

BCAT1

The branched chain amino acid (BCAA) pathway and high levels of BCAA transaminase 1 (BCAT1) have recently been associated with aggressiveness in several cancer entities. However, the mechanistic role

NIAID Data Ecosystem30

CARM1/PRMT4 is essential for myeloid leukemogenesis but dispensable for normal hematopoiesis

急性髓系白血病

RNA-seq转录组学

We investigated the role of PRMT4 in normal and malignant hematopoiesis. We found that knockdown of PRMT4 impairs cell cycle progression, induces apoptosis, and downgretulateds E2F target genes in leu

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Supplementary Table 2 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

急性髓系白血病

转录因子调控

Transcription Factor Enrichment Analysis of MOLM13 Bulk RNA-Seq (24 Hours After Drug Treatment)

Figshare2023-07-05 更新40