Castration-resistant prostate cancer (CRPC) marks the advanced and lethal stage of prostate cancer (PCa). TRIM28, also known as KAP1, is a transcriptional regulator recently shown to promote CRPC cell
Functional annotation clustering of genes with a H3K27ac differently enriched promoter connected to transcription factors with motifs overrepresented in soleus and EDL myonuclei, respectively. Cluster
This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.
In each of the three sub-challenges the number of nodes was held constant but the number of edges and regulator nodes was not. There were five gold standard networks in each of the three sub-challenge