Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor 24b
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Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor 24b Descriptor: RAC-alpha serine/threonine-protein kinase, ~{N}-[1-methyl-2-oxidanylidene-3-[1-[[4-(5-oxidanylidene-3-phenyl-6~{H}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]benzimidazol-5-yl]propanamide Authors: Landel, I, Weisner, J, Mueller, M.P, Scheinpflug, R, Rauh, D. Deposit date: 2018-08-28 Release date: 2019-02-20 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt. Chem Sci, 10, 2019
创建时间:
2018-08-28



