Protein lysates were collected from WT or Xrn1 ko A549 cells and HEKT293T ishXrn1 cells treated with doxycycline for 3-4 days or left untreated. They were then probed with antibodies against Xrn1 or b
This file provides further information on materials and methods used in this study, as well as one supplemental table, and images of western blot used in the figure
aEvaluated by densitometry of PAGE Gels Stained with Coomassie Blue R-250 bPurified according to cGMP standards ND = not done WT = wild type CH = codon harmonized
Figure S1: Cig2 protein levels remain consistent despite a reduction in Cdc13 activityFigure S2: Cdc13 protein levels are higher than Cig2 protein levels in cycling cellsFigure S3: Elevated constituti
