A previously identified anti-rheumatic compound α-mangostin (MAN) possesses notable metabolism regulatory properties. In this study, we investigated the immune implication of MAN-altered fat metabolis

NIAID Data Ecosystem70

Roles of Nr4a family transcription factors in Th and Treg cell differentiation from Tnaive cells. Roles of Nr4a family transcription factors in Th and Treg cell differentiation from Tnaive cells

T细胞分化

转录因子调控

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem70

Essential functions of the transcription factors TCF1 and SOX13 in gdT cell development (Sox13hi and Sox13lo). Mus musculus

T细胞分化

转录因子调控

Innate-like gd T effector subsets are exported from the thymus as “memory-like” cells prewired for rapid, specialized function. Previously, we showed that emergent gd subsets distinguished by TCRg and

NIAID Data Ecosystem80

Gene expression profiles of FoxO4 overexpressing TH1 cells.

T细胞分化

转录因子功能基因组学

To assess the function of FoxO4 in processes of TH1 differentiation, we have performed a whole genome microarray assay to discover the significant changed genes in normal and FoxO4 overexpressing TH1

NIAID Data Ecosystem70

HIF1a-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

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