Preeclampsia Prematurity Figshare.xls

Preeclampsia is an unpredictable multiorgan disorder responsible for high maternal and perinatal morbidity and mortality. Delivery is the definite treatment to prevent complications. But the timing of delivery is a challenge. We aim to evaluate the maternal and perinatal outcomes of preeclampsia in accordance with the WHO prematurity criteria in a low-resource country. This cross-sectional study was conducted between January 2017 and December 2019 at Aga Khan University Hospital, Pakistan. All women with preterm preeclampsia were included. Pregnant women with fetal anomalies or incomplete medical records were excluded. The participants were divided into three groups based on the WHO prematurity classification: I. extremely preterm (EPB-24-27+6 weeks), II. very preterm (VPB- 28 and 31+6 weeks), III. moderate to late preterm (MLPB 32-36+6 weeks). Data was analyzed using SPSS 19.0.A total of 324 women were included. Out of these 27%, 10.8%, and 61.7% were delivered as extremely preterm, very preterm, and moderate to late preterm respectively. The mean age, history of miscarriage, parity, and multiple pregnancies were not statistically significant among the groups. 13.9% of women developed serious maternal complications. Intrauterine death occurred in 5.6% of cases, and the rate of IUD was not statistically significant among groups. The median birth weight was significantly lower in the EPB and VPB groups in comparison to the MLPB group. Out of the total, 6.3% of neonates expired, with all deaths in the extremely premature group except one baby who died after 28 weeks gestation. Our study concludes that the neonatal death rate is high when delivery is expedited before 28 weeks of gestation.