Longitudinal single-cell dynamics in chronic lymphocytic leukemia mirror disease history
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE165087
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Longitudinally sampled peripheral blood samples of 9 CLL patients were subjected to single cell RNA sequencing before and at relapse after chemotherapy with fludarabine, cyclophosphamide and rituximab (FCR); allogeneic hematopoietic stem cell transplantation (RIC allo-HSCT); ibrutinib treatment, or before and after transformation to Richter's syndrome. Mononuclear cells from peripheral blood and bone marrow were obtained from nine human patients diagnosed with chronic lymphocytic leukemia and sequenced using scRNA-seq on the 10x platform
创建时间：
2024-01-17
