Oncogenic BRAF regulates oxidative metabolism via PGC1? and MITF
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https://www.omicsdi.org/dataset/biostudies-other/S-ECPF-GEOD-38007
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We evaluated two matched human cell lines derived from primary melanocytes, termed pmel+BRAF(V600E) and pmel+BRAF(V600E)+MITF. These cells are therefore isogenic with the exception of the expression of MITF. Gene Set Enrichment Analysis of microarray data identified a highly significant induction of oxidative phosphorylation gene set in MITF expressing cells compared to control cells.
创建时间：
2016-04-14
