five

Gene expression signatures of LAPTM5 3'UTR overexpression in B cell lymphoma cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145463
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LAPTM5 3’UTR suppresses the growth of B-lymphoma cells. To investigate the underline mechanism, we used the Agilent Whole Mouse Genome Microarray 4×44K to profile the differential expressed genes. Ectopic expression of LAPTM5 3’UTR in B-lymphoma cells 38B9 led to upregulation of 225 genes and downregulation of 350 genes with a 2-fold or greater changes compare with empty vector control cells. The differential expressed genes were measured in 3 LAPTM5 3’UTR overexpression 38B9 cells samples and 3 empty vector control 38B9 cells samples. Three independent cells infection experiments were performed at each time.
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2020-02-23
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