E-cigarette Aerosol Reduces Left Ventricular Function in Adolescent Mice

Purpose: to determine the cardiac complications of vaping in adult (3 month old) and juvenile (3 week old) FVB mice. Methods: mice were exposed to filtered air or vape with or without nicotine for 4 hrs/day, 5 days/week for a total of 3 months time. RNA-seq. was conducted on RNA isolated from the left ventricle of mice from each group. mRNA profiles of cardiac tissue from mice exposed to e-cigarette vapor