Crystal structure of P21-activated kinase 4 in complex with an inhibitor compound 29
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Crystal structure of P21-activated kinase 4 in complex with an inhibitor compound 29 Descriptor: N~2~-[(7-chloro-1H-benzimidazol-6-yl)methyl]-N~4~-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine, Serine/threonine-protein kinase PAK 4 Authors: Rouge, L, Wang, W. Deposit date: 2015-05-22 Release date: 2015-07-01 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.903 Å) Cite: Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors. J.Med.Chem., 58, 2015
结合抑制剂化合物29的P21激活激酶4（P21-activated kinase 4, PAK4）的晶体结构 描述符：N²-[(7-氯-1H-苯并咪唑-6-基)甲基]-N⁴-(5-环丙基-1H-吡唑-3-基)嘧啶-2,4-二胺、丝氨酸/苏氨酸蛋白激酶PAK4 作者：Rouge, L、Wang, W 保藏日期：2015-05-22 发布日期：2015-07-01 最后修改日期：2024-11-06 实验方法：X射线衍射（分辨率2.903 Å） 引用文献：《I组选择性p21激活激酶抑制剂的结构导向设计》，J.Med.Chem.，58卷，2015年
