Genetically engineered Carbonic Anhydrase IX in complex with Dorzolamide

Genetically engineered Carbonic Anhydrase IX in complex with Dorzolamide Descriptor: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 2, ZINC ION Authors: Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, McKenna, R. Deposit date: 2013-08-05 Release date: 2013-11-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.658 Å) Cite: Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases. Bioorg.Med.Chem., 21, 2013本数据集为基因工程化碳酸酐酶IX（Carbonic Anhydrase IX）与多佐胺（Dorzolamide）的复合物。组成描述：(4S-反式)-4-(乙氨基)-5,6-二氢-6-甲基-4H-噻吩并[2,3-b]噻喃-2-磺酰胺-7,7-二氧化物、碳酸酐酶2（Carbonic anhydrase 2）、锌离子（ZINC ION）。作者：Pinard, M.P.、Boone, C.D.、Rife, B.D.、Supuran, C.T.、McKenna, R.。保藏日期：2013-08-05。发布日期：2013-11-06。最后修改日期：2024-02-28。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.658埃。引用文献：布林佐胺与多佐胺抑制人碳酸酐酶的相互作用结构研究，《Bioorg.Med.Chem.》，21卷，2013年