Asperterpenols A and B, New Sesterterpenoids Isolated from a Mangrove Endophytic Fungus Aspergillus sp. 085242
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https://figshare.com/articles/dataset/Asperterpenols_A_and_B_New_Sesterterpenoids_Isolated_from_a_Mangrove_Endophytic_Fungus_i_Aspergillus_i_sp_085242/2414326
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Asperterpenol A (1) and asperterpenol B (2), two novel sesterterpenoids with an unusual 5/8/6/6 tetracyclic ring skeleton, were isolated from a mangrove endophytic fungus Aspergillus sp. 085242. The structures were elucidated on the basis of spectroscopic methods and the absolute configurations determined by single-crystal X-ray diffraction analysis. Compounds 1 and 2 inhibit acetylcholinesterase with IC50 values of 2.3 and 3.0 μM, respectively.
创建时间:
2016-02-19



