Access to 27-Nortomatidine and 27-Norsoladulcidine Derivatives
收藏NIAID Data Ecosystem2026-03-11 收录
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Synthesis of (22R)- and (22S)-27-norspirosolane alkaloids from tigogenin, epismilagenin, and smilagenin is described. The alkaloids were prepared from readily available dinorcholanic lactones via their reaction with 4-chlorobutyllithium followed by substitution of chloride with azide and reductive N-cyclization under the Staudinger conditions.
创建时间:
2019-03-20



