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SET Domain of Histone-Lysine N-Methyltransferase NSD2 in Complex with Selective Inhibitor

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Protein Data Bank Japan2026-01-07 更新2026-04-04 收录
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SET Domain of Histone-Lysine N-Methyltransferase NSD2 in Complex with Selective Inhibitor Descriptor: 9-{[(2M)-5-[(3R)-3-amino-3-(pyridin-2-yl)piperidin-1-yl]-2-(3,4-difluorophenyl)pyridin-4-yl]methyl}-9H-purin-6-amine, Histone-lysine N-methyltransferase NSD2, ZINC ION Authors: Szczepski, K, Jaremko, L. Deposit date: 2024-07-29 Release date: 2025-04-30 Last modified: 2026-01-07 Method: SOLUTION NMR Cite: NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers. Nature, 649, 2026
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2024-07-29
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