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Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response

ChEBI2013-01-29 更新2026-07-21 收录

炎症反应RNA调控

TNF信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43440 数据链接链接失效反馈

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资源简介：

Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response

应用场景：

创建时间：

2013-01-29

儿科克罗恩病

TNF信号通路

Background and Aims: Crohnâs disease is a debilitating chronic inflammatory disorder of the mammalian gastrointestinal tract. While current therapeutic interventions using anti-TNF biologics show lo

DataONE2022-02-19 更新80

Single-cell RNA-seq data of human Tregs treated with TNFR2 agonist antibody

Treg细胞免疫调节

TNF信号通路

Tumor necrosis factor receptor 2 (TNFR2), a membrane-bound tumor necrosis factor receptor expressed by regulatory T cells (Tregs), participates in Treg proliferation. Although a specific TNFR2 pathway

NIAID Data Ecosystem50

Wang et al TNFR1 signaling connects inflammation to impaired fatty acid oxidation to drive intestinal stem cell aging Supporting data and code

干细胞衰老

TNF信号通路

Files contain raw R code for RNAseq analysis in intestinal organoids obtained from young mice and either treated with vehicle, or TNF at a dose of 10 or 50ng/mL. Old vehicle treated are also included.

NIAID Data Ecosystem20

Crystal structure of the complex between the N-terminal domain of TRADD and the TRAF domain of TRAF2

蛋白质结构解析

TNF信号通路

Crystal structure of the complex between the N-terminal domain of TRADD and the TRAF domain of TRAF2 Descriptor: TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAIN PROTEIN, TUMOR NECROSIS F

Protein Data Bank Japan2024-11-13 更新60

TNF induced gene expression in CD8 single positive thymocytes

细胞基因表达

TNF信号通路

TNF induced gene expression in CD8 single positive thymocytes

ChEBI2017-07-05 更新30