Acute lithium treatment does not induce NDI in PKCα KO mice.
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PKCα KO and WT mice were injected intraperitoneally with 40 mmol/kg LiCl in saline every 24 hours up to 3 or 5 days. Single animals were subsequently placed in individual metabolic cages and urine and serum were collected after 0, 3 or 5 days of daily lithium treatments. Uprot/Uosm = urinary protein/urine osmolality ratio, CrCl/BW = creatinine clearance normalized to body weight (23–25 g). Data are presented as mean ± SEM where * = pn = 6.
创建时间：
2015-12-02
