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miR-515 and migration in cancer

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NIAID Data Ecosystem2026-03-12 收录
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We performed RNA-seq analyses of both estrogen receptor-positive and negative breast cancer cells over-expressing miR-515-5p which revealed down-regulation of several transcripts coding for migration promoting proteins. Modulating the expression of such proteins and miR-515 we found that miR-515 reduced migration and metastatic behaviour through direct inhibition of such pro-metastatic genes.

创建时间:
2021-02-04
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