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Structure of CRBN TBD bound to compound C1

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Protein Data Bank Japan2025-06-25 更新2026-04-19 收录
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Structure of CRBN TBD bound to compound C1 Descriptor: (3S)-3-(6-oxo-6,8-dihydro-2H,7H-spiro[furo[2,3-e]isoindole-3,4'-piperidin]-7-yl)piperidine-2,6-dione, Protein cereblon, ZINC ION Authors: Strickland, C, Rice, C. Deposit date: 2025-04-27 Release date: 2025-05-28 Last modified: 2025-06-25 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Discovery and Characterization of PVTX-321 as a Potent and Orally Bioavailable Estrogen Receptor Degrader for ER+/HER2- Breast Cancer. J.Med.Chem., 68, 2025
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2025-04-27
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