SM2 - KEGG pathway genes - hsa.xlsx

KEGG Pathway Database (Kanehisa, 2019; Kanehisa et al., 2025; Kanehisa & Goto, 2000) was used to collect genes on insulin signaling, lipid metabolism and inflammation pathways, underlying metabolic disorders common to Alzheimer's Disease and obesity. The prefix “hsa” was selected for human data, and three search terms were inserted: “inflammation”, “insulin” or “lipid”. The pathways with general descriptions surrounding the search terms were selected (Supplementary Material 1), and the section “Gene” was exported manually. Pathways with descriptions surrounding specific diseases or molecules were excluded, as well as duplicate genes, resulting in a total of 1879 genes (Supplementary Material 2).