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Impact of SOCS1 inactivation on CAR19 antitumor activity againt Nalm6 ALL (leukemia) in NSG mice. Impact of SOCS1 inactivation on CAR19 antitumor activity againt Nalm6 ALL (leukemia) in NSG mice

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NIAID Data Ecosystem2026-03-11 收录
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SOCS1 is a new intracellular checkpoint abrogating CD4 T cells response with translational value in improving CAR T cells therapies Overall design: NSG mice bearingNalm6-luc leukemia were adoptively transferred with CD4 CAR CD8 CAR Mock orsgSOCS1 and extracted from bone marrow at day 7 and and day 28 after transfer

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2020-07-20
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