遇见数据集

Supplementary Tables

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Zenodo2024-06-09 更新2026-05-26 收录
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Supplementary Tables accompaniying the following manuscript: Adeoye et al. Systematic Analysis of Biological Processes Reveals Gene Co-expression Modules Driving Pathway Dysregulation in Alzheimer’s Disease bioRxiv : the preprint server for biology 2024.03.15.585267. 15 Mar. 2024, doi:10.1101/2024.03.15.585267. Preprint. A brief description of the file contents is as follows: Supplementary Table 1. Sample metadata for all 20 donors, including post-mortem neuropathological assessments, clinical evaluations, and pathological grouping. Supplementary Tables 2—4. The table of p-values and log fold changes for all genes included in the differential analysis test across all brain regions (MTG 2; STG 3; ETC 4) and cell types. Supplementary Table 5. Table of pathway renaming conventions. Supplementary Tables 6—8. Comprehensive documentation of the pathway analysis results for each brain region (MTG 6; SFG 7; ETC 8) with detailed statistical results (coefficient estimates and p-values) for the prioritized candidate pathways identified across major cell types. Supplementary Tables 9—11. Results from DME analysis for each brain region (MTG 9; SFG 10; ETC 11) across all cell types. Supplementary Table 12. List of overlapping dysregulated pathways along with corresponding statistics for each cell type. Supplementary Table 13. List of hub genes and hDEGs in each module for all cell types across brain regions. Overlapping hub genes are presented in Supplementary Table 14.

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