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IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis.

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NIAID Data Ecosystem2026-03-12 收录
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Igf1r signaling is required in fibroblasts to drive the formation of new alveoli, and those activities is depend upon its regulation on mechanical property of myofibroblasts via an Akt/Yap mechanism. RNA-Seq analysis of FACS sorted Rosa-EGFP cells from P6 lungs after Igf1r was deleted at P0 by Gli1creER.

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2021-02-17
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