Oncogenic biogenesis of pri-miR-17~92
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA407603
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资源简介：
The microRNAs encoded by the miR-17~92 polycistron are commonly over-expressed in cancer and orchestrate a wide range of oncogenic functions. Upon overexpression processing enzymes (Drosha and DGCR8) with partially process primary miR-17~92 generating processing intermediates. Sequencing of miRNAs expressing different levels of miR-17~92, show thatincreased miR-17~92 resulted in downregulation of polycistronic miRNAs including the tumor suppressing miR-34b/c.
创建时间：
2017-09-16
