Identification of a new FoxO1 binding site that precludes CREB binding at the glucose-6-phosphatase catalytic subunit gene promoter

Identification of a new FoxO1 binding site that precludes CREB binding at the glucose-6-phosphatase catalytic subunit gene promoter Descriptor: DNA (5'-D(*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*AP*TP*AP*GP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*CP*TP*AP*TP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*TP*CP*A)-3'), Forkhead box protein O1 Authors: Singh, P, Endrizzi, J.A, Chi, Y.-I. Deposit date: 2015-09-18 Release date: 2016-09-21 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.306 Å) Cite: Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter. J. Struct. Biol., 198, 2017

人葡萄糖-6-磷酸酶催化亚基基因启动子中可阻断环腺苷酸应答元件结合蛋白（CREB）结合的新型叉头框蛋白O1（FoxO1）结合位点的鉴定
描述符：DNA（5'-D(*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*AP*TP*AP*GP*AP*AP*A)-3'）、DNA（5'-D(*TP*TP*TP*TP*CP*TP*AP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*TP*CP*A)-3'）、叉头框蛋白O1（Forkhead box protein O1）
作者：Singh, P、Endrizzi, J.A、Chi, Y.-I.
提交日期：2015-09-18
发布日期：2016-09-21
最后修改日期：2023-09-27
实验方法：X射线衍射（2.306埃）
引用文献：晶体结构揭示人葡萄糖-6-磷酸酶催化亚基1基因启动子内存在全新的FoxO1结合位点。《J. Struct. Biol.》，198卷，2017年