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A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease
Chemokine receptor 9 (CCR9), a cell surface chemokine receptor which belongs to the G protein-coupled receptor, 7-trans-membrane superfamily, is expressed on lymphocytes in the circulation and is the
Figshare2016-04-14 更新40
Discovery of Non-prostanoid EP4 Agonists for the Treatment of Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic autoimmune disease typified by disruption of the intestinal epithelium. The prostaglandin E2 receptor EP4 is linked to intestinal homeostasis, wound repai
NIAID Data Ecosystem30
Exploration of the Gut Microbiome of Inflammatory Bowel Disease Patients in Bangladesh
In Bangladesh, the diagnostic procedure for IBD patients is complex and scarce, and doctors often prescribe broad-spectrum antibiotics based on their prior experiences in the absence of evidence-based
NIAID Data Ecosystem40
An N,N‑Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C‑Like 2‑Based Therapeutic for Inflammatory Bowel Disease
Lanthionine synthetase C-like 2 (LANCL2), a novel therapeutic target for inflammatory and autoimmune diseases and diabetes, exerts anti-inflammatory and insulin-sensitizing effects. This study reports
Figshare2016-11-15 更新30
