five

human PXR LBD bound to compound 2

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Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7n2a
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资源简介:
human PXR LBD bound to compound 2 Descriptor: 5-benzyl-2-(3-fluoro-2-hydroxyphenyl)-6-methyl-3-(2-phenylethyl)pyrimidin-4(3H)-one, Isoform 1C of Nuclear receptor subfamily 1 group I member 2 Authors: Williams, S.P, Wisely, G.B, Ramanjulu, J.M. Deposit date: 2021-05-28 Release date: 2021-08-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction. Acs Med.Chem.Lett., 12, 2021
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2021-05-28
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