Audoynaud et al. 2021

NIAID Data Ecosystem2026-03-14 收录

DNA复制叉稳定性

RNA:DNA杂交体功能

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Raw data associated with Audnoynaud et al 2021 RNA:DNA hybrid from Okazaki fragment contributes to establish the Ku-mediated barrier to replication fork degradation

创建时间：

2023-01-23

Genome-wide fork-collapse sites in MEFs from ATR inhibition [mouse]. Genome-wide fork-collapse sites in MEFs from ATR inhibition [mouse]

DNA复制叉稳定性

基因组损伤

Transient obstruction of DNA polymerase progression activates the ATR checkpoint kinase, which suppresses fork breakage, strand resection, and RPA accumulation. Herein, we use a developed DNA break-de

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Dynamics of de novo heterochromatin assembly and disassembly at replication forks ensures fork stability

DNA复制叉稳定性

组蛋白修饰

Analysis of histone PTM levels in proliferating, quiescent and HU-treated TIG3 fibroblasts. TIG3 fibroblasts were cultured in the absence or presence of HU (600 μM) for at least 6 days, rendering cell

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Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A [ChIP-seq]

DNA复制叉稳定性

环状RNA调控

The accurate processing of stalled forks by the DNA2 nuclease is pivotal for replication fork restart, as excessive degradation poses a threat to genomic stability. However, the regulation of DNA2 act

NIAID Data Ecosystem30

Genome-wide fork-collapse sites in MEFs from ATR inhibition [mouse]

DNA复制叉稳定性

ATR信号通路

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Structure and repair of replication-coupled DNA breaks

DNA复制叉稳定性

重组修复机制

Using CRISPR/Cas9 nicking enzymes, we examine the interaction between the replication machinery and single strand breaks, one of the most common forms of endogenous DNA damage. We show that replicatio

NIAID Data Ecosystem30

Audoynaud et al. 2021

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