Supplemental Material for Dirksen et al., 2020

Microbes exert immense influence on the physiology of their hosts, and <i>Caenorhaditis elegans</i> is no different. Defining the natural ecology of <i>C. elegans </i>has illustrated that microbes not only act as potential food or pathogen, but can also colonize its intestines as simple communities (or ‘microbiomes’). Based on the core natural microbiome of <i>C. elegans</i>, we present a new 12-member model microbiome (CeMbio) with a wealth of resources from robust protocols to sequenced genomes to metabolic models. These tools will open the door to investigation of any aspect of <i>C. elegans</i> biology in a more natural context.