Immune effects of different forms of bivalent vaccines against ND and IBD in chickens and effects on NDV replication

Name: Immune e ffects of d ifferent f orms of bivalent v accines a gainst ND and IBD in c hickens and e ffects on NDV r eplication
Creator: Li, Qianhui; Guo, Xiaochen; Zhang, Wenlong; Yan, Min; Liu, Ziran; Shi, Chunxu; Yin, Jiechao; Sun, Wenying; Zhu, Shengrui; Wang, Yifan; Cao, Weiyue; Liu, Peijing; Qin, Ruihan; Ren, Guiping
Published: 2024-11-12T00:00:00+08:00

Figshare2024-11-12 更新2026-04-08 收录

禽类疫苗开发

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数据链接：

https://figshare.com/articles/dataset/_b_Immune_b_b_e_b_b_ffects_of_b_b_d_b_b_ifferent_b_b_f_b_b_orms_of_b_b_bivalent_b_b_b_b_v_b_b_accines_b_b_a_b_b_gainst_ND_and_IBD_in_b_b_c_b_b_hickens_and_b_b_e_b_b_ffects_on_NDV_b_b_r_b_b_eplication_b_/26403523/3 数据链接链接失效反馈

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资源简介：

In this study, two different forms of bivalent vaccines (rClone30-VP2L and rClone30+VP2L) was developed for preventing ND and IBD. The combined vaccine rClone30+VP2L stimulated stronger immune response in the initial stage of immunization, which affected replication of NDV, thereby reducing the immune effect of rClone30. The live vector vaccine rClone30-VP2L stimulated stronger immune response in the middle and late stage of immunization, which did not affected replication of NDV, therefore, the immunization effect of rClone30-VP2L was stronger than that of rClone30+VP2L vaccine. Therefore, the live vector vaccine can be used as a safe and effective vaccine candidate for preventing IBD and ND, and it provides an idea to develop other vaccines against viral infectious diseases.

提供机构：

Li, Qianhui; Guo, Xiaochen; Zhang, Wenlong; Yan, Min; Liu, Ziran; Shi, Chunxu; Yin, Jiechao; Sun, Wenying; Zhu, Shengrui; Wang, Yifan; Cao, Weiyue; Liu, Peijing; Qin, Ruihan; Ren, Guiping

创建时间：

2024-11-12