Mutant p53 dysregulates gene transcription in hematopoietic stem and progenitor cells [RNA-seq 1]
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
We found that p53 mutant hematopoietic stem and progenitor cells are resistant to iL-1? treatment through altering inflammatory response. Overall design: To determine the mechanism by which mutant p53 HSPCs are resistant to IL-1Ã, we performed RNA-seq in wild type and mutant p53 LSKs treated with 10 ng/ml of IL-1Ã or PBS in vitro.
创建时间：
2024-03-19
