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Summary of cleavage data for intronless and mutant substrates.

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aRate constants were determined from three independent experimental trials for all substrates. bk1, the rate constant for the first nicking reaction that generates nicked intermediate from circular substrate (expressed as the median of a 95% confidence interval, see Table S3). ck2, the rate constant for the second nicking reaction that generates the linear product (expressed as the median of a 95% confidence interval, see Table S3). dn.d. not determined.

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2011-08-22
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