Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate, Mg2+ and 1-(2-Hydroxy-2,2-bis-phosphono-ethyl)-3-phenyl-pyridinium

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate, Mg2+ and 1-(2-Hydroxy-2,2-bis-phosphono-ethyl)-3-phenyl-pyridinium Descriptor: 1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridinium, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... Authors: Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E. Deposit date: 2009-07-17 Release date: 2010-02-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. Proteins, 78, 2010

本数据集对应克氏锥虫（Trypanosoma cruzi）法尼基二磷酸合酶（farnesyl diphosphate synthase）同源二聚体与异戊烯基焦磷酸（isopentenyl pyrophosphate）、Mg²+及1-(2-羟基-2,2-二膦酰基乙基)-3-苯基吡啶鎓形成的复合物。配体描述：1-(2-羟基-2,2-二膦酰基乙基)-3-苯基吡啶鎓、3-甲基丁-3-烯基三氢二磷酸、法尼基焦磷酸合酶……作者：Amzel, L.M.、Huang, C.H.、Gabelli, S.B.、Oldfield, E. 存档日期：2009-07-17 发布日期：2010-02-09 最后修改日期：2024-02-21 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.2埃（Å）。引用文献：《含氮双膦酸盐（N-BPs）与克氏锥虫法尼基二磷酸合酶同源二聚体的结合作用》，Proteins，第78卷，2010年。