High-throughput characterization of autism-associated loci
收藏NIAID Data Ecosystem2026-05-01 收录
官方服务：
资源简介：
High throughput characterization of cis-regulatory sequences.
应用场景：
创建时间：
2023-04-22
相关数据集
Transcriptional silencers in Drosophila serve a dual role as transcriptional enhancers in alternate cellular contexts. Gisselbrecht et al.
A major challenge in biology is to understand how complex gene expression patterns are encoded in the genome. While transcriptional enhancers have been studied extensively, few transcriptional silence
Mendeley Data2024-01-31 更新60
Massively parallel cis-regulatory analysis in the mammalian central nervous system. Massively parallel cis-regulatory analysis in the mammalian central nervous system
Cis-regulatory elements (CREs, e.g., promoters and enhancers) regulate gene expression, and variants within CREs can modulate disease risk. Next-generation sequencing has enabled the rapid generation
NIAID Data Ecosystem50
CRISPRi screen of prostate cancer associated risk cis-regulatory elements [CRISPRi]. CRISPRi screen of prostate cancer associated risk cis-regulatory elements [CRISPRi]
Prostate cancer (PCa) associated risk SNPs are enriched in cis-regulatory elements (CREs). In this study, we screened 260 CREs that contain at least one PCa risk SNP for essentiality in V16A, 22Rv1 an
NIAID Data Ecosystem30
Additional file 8 of Autism-associated protein POGZ controls ESCs and ESC neural induction by association with esBAF
Additional file 8. POGZ targets and down-regulated genes in Figure 4F.
Figshare2022-06-02 更新50
TBR1 Regulates Autism Risk Genes in the Developing Neocortex
Exome sequencing studies have identified multiple genes harboring de novo loss-of-function (LoF) variants in individuals with autism spectrum disorders (ASD), including TBR1, a master regulator of cor
NIAID Data Ecosystem30
