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Structure of the kinase domain of human RIPK2 in complex with ponatinib

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Structure of the kinase domain of human RIPK2 in complex with ponatinib Descriptor: 1,2-ETHANEDIOL, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 Authors: Canning, P, Krojer, T, Bradley, A, Mahajan, P, Goubin, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. Deposit date: 2013-09-30 Release date: 2013-10-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors. Chem. Biol., 22, 2015
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2013-09-30
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