Structure of the kinase domain of human RIPK2 in complex with ponatinib
收藏资源简介：
Structure of the kinase domain of human RIPK2 in complex with ponatinib Descriptor: 1,2-ETHANEDIOL, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 Authors: Canning, P, Krojer, T, Bradley, A, Mahajan, P, Goubin, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. Deposit date: 2013-09-30 Release date: 2013-10-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors. Chem. Biol., 22, 2015
人类RIPK2（受体相互作用丝氨酸/苏氨酸蛋白激酶2，Receptor-Interacting Serine/Threonine-Protein Kinase 2）激酶结构域与普纳替尼（ponatinib）复合物的结构 描述符：1,2-乙二醇、3-(咪唑并[1,2-b]哒嗪-3-基乙炔基)-4-甲基-N-{4-[(4-甲基哌嗪-1-基)甲基]-3-(三氟甲基)苯基}苯甲酰胺、受体相互作用丝氨酸/苏氨酸蛋白激酶2 作者：Canning P、Krojer T、Bradley A、Mahajan P、Goubin S、von Delft F、Arrowsmith C.H、Edwards A.M、Bountra C、Bullock A. 沉积日期：2013-09-30 发布日期：2013-10-16 最后修改日期：2023-12-20 实验方法：X射线衍射（2.75 Å） 引用文献：《NOD-RIPK2介导的炎性信号通路受临床相关II型激酶抑制剂抑制》，载于《Chem. Biol.》2015年第22卷
