首页/数据集/TFRC promotes ferroptosis to suppress breast cancer bone metastasis via the activation of HIF 1 pathway

TFRC promotes ferroptosis to suppress breast cancer bone metastasis via the activation of HIF 1 pathway

NIAID Data Ecosystem2026-05-10 收录

乳腺癌转移

铁死亡机制

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP645988 数据链接链接失效反馈

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资源简介：

TFRC inhibits bone metastasis in breast cancer by promoting ferroptosis via HIF 1 activation, highlighting its potential as a therapeutic target.

应用场景：

创建时间：

2025-11-18

转录调控机制

乳腺癌转移

Yes Associated Protein (YAP) and Myocardin Related Transcription Factor (MRTF) play similar roles and crosstalk in directing the transcriptional responses to chemical and physical extracellular cues.

NIAID Data Ecosystem50

Ferroptosis associated proteins in NGLY1 -KO (KO-1) HepG2 cells. Proteomic analysis of ferroptosis associated protein expression levels within NGLY1 -KO (KO-1) HepG2 cells compared to WT HepG2 cells (n = 3).

铁死亡机制

蛋白质组学分析

Ferroptosis associated proteins in NGLY1-KO (KO-1) HepG2 cells. Proteomic analysis of ferroptosis associated protein expression levels within NGLY1-KO (KO-1) HepG2 cells compared to WT HepG2 cells (n

NIAID Data Ecosystem20

Comprehensive cognition of yak ( Bos grunniens ) AIFM2 gene and its anti-ferroptosis role in bisphenol A-induced fetal fibroblast model

铁死亡机制

双酚A毒性

Apoptosis-inducing factor mitochondrion-associated 2 (AIFM2) has been identified as a gene with anti-ferroptosis properties. To explore whether AIFM2 exerts anti-ferroptosis role in yaks (Bos grunnien

NIAID Data Ecosystem10

DataSheet_10_High expression level of the FTH1 gene is associated with poor prognosis in children with non-M3 acute myeloid leukemia.zip

AML预后标志物

铁死亡机制

Acute myelogenous leukemia (AML) is a disease that severely affects the physical health of children. Thus, we aimed to identify biomarkers associated with AML prognosis in children. Using transcriptom

NIAID Data Ecosystem30

DataSheet_1_Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.zip

胰腺癌治疗

铁死亡机制

PurposeThe anti-tumour effect of Huaier has been demonstrated in a variety of tumours. Ferroptosis is a newly identified type of programmed cell death accompanied by the accumulation of reactive oxyge

NIAID Data Ecosystem20

TFRC promotes ferroptosis to suppress breast cancer bone metastasis via the activation of HIF 1 pathway

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