Data expressed as the minimal lethal dose for 50% of cells (MDL50), used to calculate the selectivity index against either cell. *Selectivity index = MDL50//IC50.
In an effort to identify novel anti-cancer agents, we employed a well-established High Throughput Screening (HTS) assay to assess the cytotoxic effect of compounds within the ChemBridge DIVERSet Libra
aThe verotoxin titer was expressed as the reciprocal of the highest sample dilution which caused 50% cell detachment after 24 h of incubation. bStx concentration in the supernatant of infected THP-1 m
