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Hedopeptolide, a NO Production Inhibitor from the Marine Cyanobacterium <i>Okeania</i> sp.

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NIAID Data Ecosystem2026-05-02 收录
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A novel 19-membered cyclic depsipeptide, hedopeptolide (1), was isolated from Okeania sp., a marine cyanobacterium collected in Okinawa, Japan. Its gross structure was determined by spectroscopic analyses, and the absolute configuration of the chiral centers was determined by single-crystal X-ray diffraction analysis following crystallization. Hedopeptolide (1) inhibited the lipopolysaccharide-induced nitric oxide production in RAW264.7 cells.

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2025-03-27
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