five

PPAR-delta and alcohol-related liver disease

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA597350
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资源简介:
Chronic alcohol-related liver disease is associated with dysregulation of bile acid metabolism and gut barrier dysfunction. PPAR-delta agonists are key metabolic regulators and anti-inflammatory agents. In this project, we evaluated the effects of the selective PPAR-delta agonist seladelpar MBX-8025 on the gut barrier function and bile acid metabolism in a mouse model of ethanol-induced liver disease.
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2019-12-23
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