CD47 blocking antibody confers exercise effects by activating AMPK and improving mitochondrial energetics of skeletal muscle. CD47 blocking antibody confers exercise effects by activating AMPK and improving mitochondrial energetics of skeletal muscle

We report transcript profiles from skeletal muscle tissues of CD47-/-, wild-type sedentary and exercise group mice that exercise continuously for 8 weeks, 6 days a week, at a speed of 15 m/min for 1 hour per day. We found that the transcripts of CD47-/- mice were more similar to exercise mice. Overall design: For the mouse dataset, skeletal muscle tissue was taken for RNA-Seq analysis after overnight starvation treatment of sedentary WT, CD47-/- and exercise mice under a normal diet.