Pharmacokinetics profile of Lactodoxonano, Apodoxonano and Doxo.

Values in the parenthesis indicates the concentration of doxorubicin in micrograms per ml of blood/per gram of tissue; *value of t1/2β. Pharmacokinetic parameters. AUC: The integral of the concentration-time curve (after a single dose or in steady state). AUMC: Partial area under the moment curve between t start and t end. t ½: The time required for the concentration of the drug to reach half of its original value. In serum, t1/2α is referred duirngdistribution phase and t1/2β during elimination phases. Cmax :The peak plasma concentration of a drug after IV administration. Tmax :Time to reach Cmax.