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Dissecting the dynamics of signaling events in the BMP,WNT and NODAL cascade during self-organized fate patterning in human gastruloids

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP221734
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资源简介:
To determine the in vivo cellular identity of BMP-treated human embryonic stem cells (hESCs), we performed bulk RNA sequencing data of hESCs under pluripotency and BMP-treated conditions. Our analyses show that BMP-treated hESCs resemble human trophoblast cells in vivo. Overall design: mRNA profiles of four different samples, each with two biological replicates. Samples: 1) hESCs in mTeSR1 for 48h, 2) hESCs in mTeSR1+BMP4 for 48h, 3) hESCs in mTeSR1+BMP4+IWP2 for 48h, 4) hESCs in mTeSR1+BMP4+SB for 48h
创建时间:
2019-11-13
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