Transcriptome-wide GRS analysis.

Caption: gene_id = ENSEMBL gene id, beta = effect estimate, se = standard error, pval (not adjusted for multiple testing), R2 = proportion of variance explained by serum ACE wGRS, z-score = test-statistic for association between serum ACE wGRS and gene expression, p.adjust = p-value adjusted for multiple testing using a Bonferroni correction, chr = chromosome of gene, start = location of start of gene, end = location of end of gene, strand = coding strand, gene_type = type of gene examined. ACE, angiotensin-converting enzyme; GRS, genetic risk score; wGRS, weighted genetic risk score. (XLSX)