Summary of functional, morphological and immunological alterations in gene-deleted mouse strains compared to the C57Bl/6 WT group.
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Mechanical hyperalgesia was significantly attenuated in Tac4−/− and Tacr1−/− animals, while oedema formation did not differ in any strain. Inflammatory reactions characterised by the histological alterations and changes of cytokine levels were significantly reduced in Tac4−/− and Tac1−/−/Tac4−/− groups.
创建时间:
2015-12-02



