Effect of PDE inhibition on basal submembrane cAMP signal in RASMCs.
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Submembrane cAMP measurements were conducted in cultured RASMCs cells using the FRET-based cAMP sensor pm-Epac2-camps. The % increase in CFP/YFP ratio induced by the different PDE inhibitors or the vehicle was calculated after a 3 min-incubation. Data are mean±SEM of 8–14 independent cells as indicated. *** P<0.001 versus vehicle; ## P<0.01 versus Cil and versus Ro.
创建时间：
2012-10-18
