Chemotherapy-induced changes in circulating miRNAs concentrations.

1The change plasma miRNA concentrations from baseline to after treatment with decitabine and carboplatin.2,3Subgroup analysis of non-responsive subjects (progressed before 7 cycles of therapy) and responsive subjects (did not progress before 7 cycles of therapy), respectively.4Plasma miRNA concentrations are fold differences between responders and non-responders using the after chemotherapy treatment miRNA concentrations. Non-responsive subjects are those that had 6 months prior to progression of ovarian cancer based on RECIST.*paPaired T-testbT-test.Chemotherapy-induced changes in circulating miRNAs concentrations.