Transcription-coupled DNA-protein crosslink repair
收藏NIAID Data Ecosystem2026-05-01 收录
官方服务:
资源简介:
The goal is to understand how cells remove DNA-protein crosslinks in transcribed regions of genome.
应用场景:
创建时间:
2023-08-04
相关数据集
Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging
Original data for manuscript "Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging"
Mendeley Data2020-07-09 更新30
SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways
Several endogenous metabolites, environmental agents, and therapeutic drugs promote formation of covalent DNA-protein crosslinks (DPCs). Persistent DPCs pose a serious threat to genome integrity and a
NIAID Data Ecosystem20
Transitions in the coupling of transcription and nucleotide excision repair within RNA polymerase II-transcribed genes of Saccharomyces cerevisiae
The molecular mechanism of transcription-coupled nucleotide excision repair in eukaryotes is poorly understood. The identification of the dual role of basal transcription factor TFIIH in DNA repair an
PubMed Central1997-07-22 更新10
Reversible 5-formyluracil DNA-histone crosslinks: formation and biological effects
5-Formyluracil (5fU) is a vital DNA modification that widely presents in cells and organisms. A unique feature of 5fU is the presence of a potentially reactive aldehyde group in its structure, which c
NIAID Data Ecosystem30
STK19 accelerates the clearance of lesion-stalled RNAPII to facilitate transcription-coupled DNA repair. STK19 accelerates the clearance of lesion-stalled RNAPII to facilitate transcription-coupled DNA repair
Transcription-coupled DNA repair (TCR) removes bulky DNA lesions impeding RNA polymerase II (RNAPII) transcription. Recent studies have outlined the stepwise assembly of TCR factors CSB, CSA, UVSSA, a
NIAID Data Ecosystem10



